CAR Engineered γδ T Cell Development ServicesOnline Inquiry
Chimeric antigen receptor (CAR)-engineered γδ T cell represents a new type of immunotherapy that utilizes T cell immunity against various kinds of tumors. There is increasing evidence to report the exciting results of CAR-modified γδ T cells in the treatment of cancer. γδ T cells, an important population of T cells, have several advantages in fighting tumor cells such as strong cytotoxic effects on tumor cells. They are considered as promising candidates for developing cell immunotherapy. γδ T cells engineered to express a CAR can recognize a certain tumor antigen and activate immune cells against tumor cells, which paves a new way for tumor treatment.
Creative Biolabs has organized a staff of outstanding scientists who have engaged in γδ T cell research and γδ T cell based immunotherapy development for many years. We are committed to providing a full range of CAR engineered γδ T cell development services, including design and generation of CAR, CAR lentivirus production, γδ T cell preparation, transduction of activated γδ T cells with CAR-encoding lentivirus, and validation of CAR γδ T cell. Our one-stop high-quality services will accelerate the development of CAR-γδ T cells for tumor treatment.
Screening and sequencing of scFvs that are specific to the cancer antigens
Design and construct scFv-CAR of different varieties such as mono-scFv CAR and dual scFv CAR
Validation of specificities and activities for scFv-CAR constructs
Production of high titer lentivirus for scFv-CAR constructsγδ T-Cell Preparation for CAR Lentivirus Transduction
Isolate, activate and expand primary γδ T cells from healthy donors or patientsValidation of CAR γδ T Cells
Assay of CAR expression
CAR-γδ T cell expansion
Assay of multiplex cytokine production
Cytotoxicity test using co-culture of target cells and CAR-γδ T cells
Testing efficacy, viability, bio-distribution, and toxicity of CAR-γδ T cells using animal modelCAR Transduction for Engineered γδ T Cell
Transduction of activated γδ T cells with CAR-encoding lentivirus
Various transfection technology available
Transfection method tailored for different cell types
- An excellent expert team support whole-process technical trace and direction
- One-stop services from project design to the best results delivery
- Rich experience for the development of CAR-γδ T cells
- A variety of solutions for developing CAR-γδ T cell
- Advanced analysis platforms to ensure the high-quality CAR-γδ T cell delivery
Our high-quality services will accelerate the process of development of CAR γδ T cells. Contact us for more information about our CAR engineered γδ T cell development services.